Zesty Cajun Garlic Parmesan Chicken

Featured in: All-American Desserts

This vibrant Cajun-inspired pasta dish features juicy chicken, cheese-stuffed tortellini, and a luxurious garlic Parmesan cream sauce, delivering a punch of flavor and comfort in every bite. Aromatics such as onion, garlic, and bell pepper are sautéed to form a savory base, accented with Cajun spices and smoked paprika for a gentle heat. Fresh parsley and extra Parmesan add a finishing touch, making this easy skillet meal ideal for fast weeknight cooking. Serve with crusty bread and a glass of crisp white wine for a satisfying fusion of American and Italian flavors.

Updated on Sat, 08 Nov 2025 13:29:00 GMT
Zesty Cajun Garlic Parmesan Chicken Tortellini in a creamy sauce, garnished with fresh parsley.  Save
Zesty Cajun Garlic Parmesan Chicken Tortellini in a creamy sauce, garnished with fresh parsley. | dashofstates.com

A vibrant and flavorful pasta dish featuring tender chicken, cheesy tortellini, and a creamy Cajun garlic Parmesan sauce. Perfect for a quick weeknight meal with a spicy kick. Preparation Time: 15 minutes Cooking Time: 25 minutes Total Time: 40 minutes Category: Main Dish Difficulty: Easy Cuisine: American/Italian Fusion Yield: 4 servings Diet: Contains Dairy

When I first made this recipe for my family, the spicy Cajun sauce was a hit even with the picky eaters. They especially loved the creamy Parmesan coating every bite of tortellini and chicken!

Ingredients

  • Boneless, skinless chicken breasts: 2 large, cut into bite-sized pieces
  • Refrigerated cheese tortellini: 500 g (18 oz)
  • Garlic: 3 cloves, minced
  • Red bell pepper: 1 small, diced
  • Yellow onion: 1 small, diced
  • Heavy cream: 1 cup (240 ml)
  • Freshly grated Parmesan cheese: 1/2 cup (50 g)
  • Unsalted butter: 2 tablespoons
  • Cajun seasoning: 1 tablespoon
  • Smoked paprika: 1/2 teaspoon
  • Black pepper: 1/2 teaspoon
  • Salt: 1/2 teaspoon, plus more to taste
  • Olive oil: 2 tablespoons
  • Chopped fresh parsley: 2 tablespoons, for garnish
  • Optional extra grated Parmesan: For serving

Instructions

Cook Tortellini:
Bring a large pot of salted water to a boil. Cook tortellini according to package instructions. Drain and set aside.
Prepare Chicken:
Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add chicken pieces, season with half the Cajun seasoning, salt, and pepper. Sauté until browned and cooked through, about 5 minutes. Remove chicken from skillet and set aside.
Sauté Vegetables:
In the same skillet, add remaining olive oil and butter. Sauté onion and bell pepper for 3 minutes until softened. Add garlic and cook for 30 seconds until fragrant.
Make Sauce:
Sprinkle in remaining Cajun seasoning and smoked paprika. Stir, then pour in the heavy cream. Bring to a gentle simmer, stirring frequently.
Add Parmesan:
Add Parmesan cheese and stir until melted and sauce is smooth. Taste and adjust seasoning if needed.
Combine Chicken and Tortellini:
Return chicken to the skillet, along with cooked tortellini. Toss gently to coat everything in the sauce.
Finish:
Cook for an additional 2 minutes until heated through.
Serve:
Serve garnished with fresh parsley and extra Parmesan if desired.
A vibrant bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini with savory spices and cheese.  Save
A vibrant bowl of Zesty Cajun Garlic Parmesan Chicken Tortellini with savory spices and cheese. | dashofstates.com

My kids always ask for seconds when I serve this saucy tortellini. It is now a regular favorite for quick family dinners and special occasions alike.

Required Tools

Large pot, large skillet, chefs knife, cutting board, wooden spoon or spatula, measuring cups and spoons

Allergen Information

Contains wheat, milk, and eggs. Always check tortellini packaging for ingredient updates.

Nutritional Information

Per serving: Calories 620, Total Fat 29 g, Carbohydrates 53 g, Protein 38 g

Delicious Zesty Cajun Garlic Parmesan Chicken Tortellini served with crusty bread for a perfect meal. Save
Delicious Zesty Cajun Garlic Parmesan Chicken Tortellini served with crusty bread for a perfect meal. | dashofstates.com

This dish is extra comforting and comes together quickly on busy nights. Try adding fresh basil for a bright finish.

Recipe FAQ

Can I substitute shrimp for chicken?

Absolutely. Swap chicken with shrimp for a seafood option. Cook shrimp briefly until just pink and tender.

What type of tortellini works best?

Use cheese tortellini for a creamy finish, or try spinach or mushroom-filled for added depth.

How spicy is the dish?

The Cajun seasoning offers moderate spice. Adjust heat by adding cayenne or red pepper flakes to taste.

Can I make the sauce ahead?

The creamy sauce is best prepared fresh, but you can chop ingredients ahead to save time.

What can I serve alongside?

Pair with crusty bread to soak up sauce and complement with a crisp white wine such as Sauvignon Blanc.

Is this suitable for vegetarians?

Omit chicken and use extra vegetables or use plant-based sausage for a vegetarian-friendly version.

Zesty Cajun Garlic Parmesan Chicken

Tender chicken and cheesy tortellini in creamy Cajun garlic Parmesan sauce. Easy, bold, and perfect for busy nights.

Prep duration
15 min
Cook duration
25 min
Complete duration
40 min
Created by Jordan Miller


Complexity Easy

Heritage American/Italian Fusion

Output 4 Portions

Nutritional considerations None specified

Components

Proteins

01 2 large boneless, skinless chicken breasts, cut into bite-sized pieces

Pasta

01 18 ounces refrigerated cheese tortellini

Vegetables & Aromatics

01 3 cloves garlic, minced
02 1 small red bell pepper, diced
03 1 small yellow onion, diced

Dairy

01 1 cup heavy cream
02 1/2 cup freshly grated Parmesan cheese
03 2 tablespoons unsalted butter

Spices & Seasonings

01 1 tablespoon Cajun seasoning
02 1/2 teaspoon smoked paprika
03 1/2 teaspoon black pepper
04 1/2 teaspoon salt, plus more to taste

Oils & Garnish

01 2 tablespoons olive oil
02 2 tablespoons chopped fresh parsley
03 extra grated Parmesan cheese, optional, for serving

Method

Phase 01

Cook Tortellini: Bring a large pot of salted water to a boil. Add tortellini and cook according to the package instructions until al dente. Drain and set aside.

Phase 02

Sauté Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Arrange chicken pieces in a single layer and season with half the Cajun seasoning, salt, and pepper. Sauté until browned on all sides and cooked through, about 5 to 7 minutes. Remove the chicken from the skillet and set aside.

Phase 03

Sauté Vegetables: In the same skillet, add the remaining tablespoon olive oil and butter. Add diced onion and red bell pepper; sauté for 3 to 4 minutes until vegetables are softened. Add minced garlic and cook for 30 seconds until aromatic.

Phase 04

Prepare Sauce: Sprinkle in remaining Cajun seasoning and smoked paprika, stirring to coat the vegetables. Pour in heavy cream and bring to a gentle simmer, stirring frequently until the mixture is well blended.

Phase 05

Finish Cream Sauce: Stir in Parmesan cheese and mix until fully melted and sauce is smooth. Taste and adjust seasoning with additional salt or pepper if desired.

Phase 06

Combine Chicken and Pasta: Return the sautéed chicken to the skillet along with the cooked tortellini. Gently toss all components in the creamy sauce to ensure thorough coating.

Phase 07

Final Heating: Allow the mixture to cook for an additional 2 to 3 minutes until everything is heated through.

Phase 08

Serve and Garnish: Divide onto serving plates and garnish with fresh parsley and extra Parmesan cheese as desired.

Necessary tools

  • Large pot
  • Large skillet
  • Chef's knife
  • Cutting board
  • Wooden spoon or spatula
  • Measuring cups and spoons

Allergy details

Review each component for potential allergens and seek professional medical guidance if you're uncertain.
  • Contains wheat (tortellini), milk (cream, Parmesan, butter), and eggs (verify tortellini ingredients). Always check packaging for detailed allergen information.

Nutrient breakdown (each portion)

These figures are approximate and shouldn't replace professional health advice.
  • Energy: 620
  • Fats: 29 g
  • Carbohydrates: 53 g
  • Proteins: 38 g