Artichoke Spinach Grilled Cheese

This artichoke spinach grilled cheese combines the comfort of a classic sandwich with the rich flavors of spinach-artichoke dip. Cream cheese, mozzarella, Monterey Jack, and Parmesan blend with sautéed spinach and chopped artichoke hearts for a luxurious filling. Spread between buttered sourdough slices and pan-grilled until the bread is golden and the cheese melts into creamy perfection. Ready in just 25 minutes, it's an easy vegetarian main dish that serves four.

Updated on Tue, 20 Jan 2026 15:03:00 GMT
Golden, crispy sourdough slices encase melted cheese with creamy spinach and artichoke dip filling in this Artichoke Spinach Grilled Cheese.  Save
Golden, crispy sourdough slices encase melted cheese with creamy spinach and artichoke dip filling in this Artichoke Spinach Grilled Cheese. | dashofstates.com

My neighbor knocked on the door one rainy Tuesday holding a jar of artichoke hearts she didn't know what to do with. I had leftover spinach dip in the fridge and a loaf of sourdough going stale. We stood in the kitchen experimenting, and twenty minutes later we were biting into something that tasted like restaurant indulgence but required almost no skill. That accidental afternoon became my blueprint for comfort food that impresses without intimidation.

I made these sandwiches for my book club after someone canceled our restaurant reservation last minute. Everyone arrived expecting cheese and crackers, but I pulled out these golden, oozing sandwiches instead. The room went quiet except for the sound of biting through crisp bread. One friend asked if I'd ordered takeout, and I just smiled and said it took fifteen minutes. That night, three people texted me for the recipe before they even got home.

Ingredients

  • Fresh spinach, chopped: Fresh spinach wilts beautifully into the filling and adds a bright green color, but frozen works just as well if you squeeze out every drop of water first.
  • Canned or jarred artichoke hearts, drained and chopped: These bring a tangy, briny flavor that balances the richness of the cheese, and I always keep a jar in the pantry for emergencies like this.
  • Cream cheese, softened: This is the glue that holds everything together and makes the filling spreadable, so let it sit on the counter for at least twenty minutes before mixing.
  • Shredded mozzarella cheese: Mozzarella melts into stretchy, gooey perfection and doesn't overpower the other flavors.
  • Shredded Monterey Jack or Swiss cheese: I switch between these depending on my mood; Monterey Jack is mild and creamy, while Swiss adds a slight nuttiness.
  • Grated Parmesan cheese: A little Parmesan goes a long way, adding a salty, umami punch that makes the filling taste more complex than it really is.
  • Unsalted butter, softened: Butter on the outside of the bread is non-negotiable for that golden, crispy crust that crackles when you bite into it.
  • Sourdough bread: The slight tang of sourdough complements the artichokes perfectly, and the sturdy texture holds up to all that creamy filling without getting soggy.
  • Small garlic clove, minced: One clove is enough to add a whisper of garlic without making the sandwich taste like garlic bread.
  • Black pepper: Freshly cracked pepper adds a gentle heat and sharpness that wakes up the creamy filling.
  • Crushed red pepper flakes (optional): I add these when I want a tiny kick of heat that sneaks up on you after the first bite.
  • Pinch of salt: The cheeses and artichokes are already salty, so a pinch is all you need to bring everything into balance.

Instructions

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Mix the Filling:
In a mixing bowl, combine the cream cheese, mozzarella, Monterey Jack (or Swiss), Parmesan, spinach, artichokes, minced garlic, black pepper, red pepper flakes, and a pinch of salt. Stir everything together until it looks like a thick, creamy dip with flecks of green and tan throughout.
Assemble the Sandwiches:
Lay out all eight slices of sourdough and spread the artichoke-spinach mixture generously onto four of them. Top each with a second slice of bread, pressing down gently so the filling spreads to the edges.
Butter the Outsides:
Use softened butter to coat the outside of each sandwich on both sides, making sure to reach all the way to the crusts. This is what creates that shatteringly crisp, golden surface.
Cook Until Golden:
Heat a large skillet or griddle over medium heat and place the sandwiches in the pan, working in batches if needed. Cook for 3 to 4 minutes per side, pressing gently with a spatula, until the bread turns deep golden brown and the cheese starts to ooze out the sides.
Rest and Serve:
Remove the sandwiches from the skillet and let them rest for one minute before slicing. This brief pause helps the filling set just enough so it doesn't all spill out when you cut in.
Artichoke Spinach Grilled Cheese rests on a cutting board, sliced to reveal layers of gooey melted mozzarella and Monterey Jack inside.  Save
Artichoke Spinach Grilled Cheese rests on a cutting board, sliced to reveal layers of gooey melted mozzarella and Monterey Jack inside. | dashofstates.com

One Sunday morning, my daughter wandered into the kitchen while I was making these for lunch. She watched me press the spatula down and listened to the sizzle, then asked if we could have them for breakfast next time. Now we sometimes skip the pancakes and start the day with these instead, paired with fresh orange juice. It's become our little rebellion against breakfast rules, and honestly, it feels more indulgent than any waffle ever did.

Choosing Your Bread

Sourdough is my first choice because its tangy flavor echoes the artichokes and its firm texture holds up to the creamy filling without falling apart. I've also used ciabatta when I wanted something airier, and whole wheat when I felt like pretending to be healthy. Avoid soft sandwich bread; it turns mushy under the weight of the filling and doesn't crisp up the way you want it to.

Making It Your Own

I sometimes toss in a handful of chopped sun-dried tomatoes for a sweet-tart burst, or stir in a spoonful of pesto if I have it lying around. A friend of mine adds crumbled bacon, which I'll admit is dangerously good. You can also swap the Monterey Jack for Gruyere if you're feeling fancy, though that might push this into dinner party territory instead of Tuesday night simplicity.

Serving Suggestions

These sandwiches are rich enough to be the main event, but I usually serve them with something bright and fresh to cut through the creaminess. A simple arugula salad with lemon vinaigrette works wonders, or a bowl of tomato soup for dunking if you're leaning into full-on comfort mode. Sometimes I just slice up a few pickles and call it a day.

  • Pair with a crisp white wine or sparkling water with lemon if you want to feel a little fancy.
  • Serve alongside a handful of kettle chips for crunch and salt contrast.
  • If you have leftovers, reheat them in a dry skillet over low heat rather than the microwave to keep the bread crispy.
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This golden-grilled Artichoke Spinach Grilled Cheese pairs perfectly with a steaming bowl of tomato soup for a comforting lunch. Save
This golden-grilled Artichoke Spinach Grilled Cheese pairs perfectly with a steaming bowl of tomato soup for a comforting lunch. | dashofstates.com

This sandwich has become my answer to the question of what to make when I want something that feels special but don't have the energy for a project. It's proof that comfort food doesn't have to be complicated, and sometimes the best meals are born from a neighbor's extra jar of artichokes and a willingness to experiment.

Recipe FAQ

Can I prepare the filling ahead of time?

Yes, you can make the artichoke-spinach filling up to 2 days in advance. Store it in an airtight container in the refrigerator, then assemble and cook the sandwiches when ready.

What bread alternatives work best?

Sourdough provides excellent texture and tang, but you can use whole wheat for added fiber, brioche for richness, or gluten-free bread to accommodate dietary needs. Choose bread that toasts evenly for best results.

How do I prevent the cheese from leaking out while cooking?

Spread the filling evenly without overstuffing, and keep the heat at medium to allow the bread to cook through before the cheese fully melts. Press gently while cooking to help seal the filling inside.

Can I add other ingredients to the filling?

Absolutely. Sun-dried tomatoes, chopped scallions, roasted red peppers, or caramelized onions complement the spinach-artichoke base beautifully. Add these ingredients to taste while maintaining the filling's creamy consistency.

What's the best side dish to serve with this sandwich?

Tomato soup is a classic pairing that complements the rich, creamy filling. A crisp green salad or coleslaw also works well to balance the richness of the cheese and butter.

How do I ensure the bread gets crispy while the cheese melts?

Use medium heat and cook for 3-4 minutes per side, allowing the bread to develop a golden crust. Don't rush the cooking process, as this ensures both texture and proper melting of all the cheeses inside.

Artichoke Spinach Grilled Cheese

Decadent grilled cheese with creamy spinach-artichoke filling, perfectly melted between crispy golden sourdough bread.

Prep duration
15 min
Cook duration
10 min
Complete duration
25 min
Created by Jordan Miller


Complexity Easy

Heritage American

Output 4 Portions

Nutritional considerations Meat-free

Components

Vegetables

01 1 cup fresh spinach, chopped (or 1/2 cup frozen, thawed and drained)
02 1 cup canned or jarred artichoke hearts, drained and chopped

Dairy

01 4 oz cream cheese, softened
02 1/2 cup shredded mozzarella cheese
03 1/2 cup shredded Monterey Jack or Swiss cheese
04 1/4 cup grated Parmesan cheese
05 2 tablespoons unsalted butter, softened

Bread

01 8 slices sourdough bread

Seasonings

01 1 small garlic clove, minced
02 1/4 teaspoon black pepper
03 1/8 teaspoon crushed red pepper flakes (optional)
04 Pinch of salt

Method

Phase 01

Prepare filling mixture: In a mixing bowl, combine cream cheese, mozzarella, Monterey Jack, Parmesan, spinach, artichokes, garlic, black pepper, red pepper flakes, and salt. Mix until well blended.

Phase 02

Assemble sandwiches: Lay out sourdough slices. Spread artichoke-spinach mixture evenly onto 4 slices. Top with remaining bread slices to form sandwiches.

Phase 03

Butter sandwiches: Lightly butter the outside of each sandwich on both sides.

Phase 04

Cook sandwiches: Heat a large skillet or griddle over medium heat. Place sandwiches in the pan and cook 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Phase 05

Rest and serve: Remove from skillet, let rest 1 minute, then slice and serve warm.

Necessary tools

  • Mixing bowl
  • Spoon or spatula
  • Knife and cutting board
  • Skillet or griddle
  • Spatula for flipping

Allergy details

Review each component for potential allergens and seek professional medical guidance if you're uncertain.
  • Contains dairy (cheese, butter)
  • Contains wheat (bread)
  • May contain soy depending on bread and cheese brands

Nutrient breakdown (each portion)

These figures are approximate and shouldn't replace professional health advice.
  • Energy: 410
  • Fats: 23 g
  • Carbohydrates: 38 g
  • Proteins: 15 g